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LP PLA2 Activity

Order Code CH247
Turnaround Time 24-48 hours
Test Includes

LP PLA2 Activity

Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

SST (Tiger Top)

Preferred Specimens
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Moderate to grossly lipemic
Moderate to grossly icteri

Test Details
Clinical Significance

Lipoprotein-associated phospholipase A2 (Lp- PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events. Clinical management may include beginning or intensifying risk reduction strategies. The activity assay is an enzyme assay run on an automated chemistry platform.

Reference Ranges

≤ 225 nmol/min/mL

Alternative Names