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Lipoprotein A

Order Code CH164
Turnaround Time 24-48 hours
Test Includes

Lipoprotein A

Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

Serum Separator Tube (SST)

Preferred Specimens
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Gross lipemia
PPT potassium
EDTA (white-top) tube

Test Details
Immunoturbidimetric Assay
Clinical Significance

Cardiovascular disease (CVD) risk refinement in patients with moderate or high risk based on conventional risk factors. Lipoprotein (a) (Lp[a]) consists of an LDL particle that is covalently bound to an additional protein, apolipoprotein (a) (Apo[a]). Apo(a) has high-sequence homology with the coagulation factor plasminogen and, like LDL, Lp(a) contains apolipoprotein B100 (ApoB). Thus, Lp(a) is both proatherogenic and prothrombotic. Lp(a) is an independent risk factor for coronary heart disease (CHD), ischemic stroke, and aortic valve stenosis. Lp(a) has been referred to as “”the most atherogenic lipoprotein.”” The mechanism of increased risk is unclear but most likely involves progression of atherosclerotic stenosis via intimal deposition of cholesterol and promotion of thrombosis via homology to plasminogen.

Reference Ranges

≤ 30 mg/dL

Alternative Names