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Lipase

CPT/HCPCS 83690
Order Code CH162
Turnaround Time 24-48 hours
Test Includes

Lipase

Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

SST (Tiger Top)

Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 30 days
Frozen
Test Details
Methodology
Spectrophotometry
Clinical Significance

Investigating pancreatic disorders, usually pancreatitis. Lipases are enzymes that hydrolyze glycerol esters of long-chain fatty acids and produce fatty acids and 2-acylglycerol. Bile salts and a cofactor, colipase, are required for full catalytic activity and greatest specificity. The pancreas is the primary source of serum lipase. Both lipase and colipase are synthesized in the pancreatic acinar cells and secreted by the pancreas in roughly equimolar amounts. Lipase is filtered and reabsorbed by the kidneys. Pancreatic injury results in increased serum lipase levels.

Reference Ranges

13 – 60 IU/L