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Lactic Acid

CPT/HCPCS 83605
Order Code CH159
Turnaround Time 5 days
Test Includes

Lactic Acid

Specimen Requirements
Specimen Source
Plasma
Transport Container
(Specimen Container)

Gray-top tube

Preferred Specimens
2 mL frozen plasma
Minimum Volume (uL)
0.5 mL
Collection Instructions
(Transport Temperature)
Transport Frozen
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 72 hours
Frozen 30 days
Reject Criteria

Gross hemolysis
Grossly icteric

Special Instructions

The collected blood should be well-mixed and separated from the cells within 3 hours. Freeze plasma and ship frozen. The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for Lactate (Lactic Acid), leading to falsely low results. Sample should be collected without the use of a tourniquet; avoid hand-clenching. If a tourniquet has been used, it should be released for one minute prior to drawing blood. Collected blood should be cooled on ice immediately and separated from the cells within 3 hours. Transport Frozen.

Test Details
Methodology
Spectrophotometry (SP)
Clinical Significance

Lactic acid is the endproduct of the anaerobic metabolism of glucose. The blood lactic acid concentration is affected by its production in muscle cells and erythrocytes and its rate of metabolism in the liver. During exercise, blood lactate can increase up to ten times of normal levels.

Reference Ranges

0.4 – 1.8 mmol/L

Alternative Names
Lactate