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Chloride Serum

Order Code CH127
Turnaround Time 24 hours
Test Includes

Chloride Serum

Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

SST (Tiger Top)
Lithium Heparin/ Sodium Heparin

Preferred Specimens
Minimum Volume (uL)
.5 mL
Collection Instructions
(Transport Temperature)
Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 7 days
Frozen >1 year
Test Details
Ion-selective electrode diluted (Indirect)
Clinical Significance

Chloride is the major extracellular anion. The majority of ingested chloride is absorbed, and the excess is excreted along with other ions into the urine. Low levels of chloride are observed in the case of prolonged vomiting accompanied by the loss of hydrochloric acid (HCl), in metabolic alkalosis, in critical cases of Addison’s disease, and in kidney disease resulting in loss of salt. Elevated levels of chloride are observed in metabolic acidosis associated with prolonged diarrhea and with loss of sodium bicarbonate (NaHCO3), and in the case of renal tubular diseases in which there is a decreased excretion of hydrogen ion (H+), which causes in turn a decrease in the reabsorption of bicarbonate ion (HCO3-).

Reference Ranges

96 – 104 mmol/L (Cord)
95 – 110 mmol/L (Premature)
98 – 113 mmol/L (0 Days – 30 Days)
98 – 107 mmol/L (1 Years – 89 Years)
98 – 111 mmol/L (90 Years – No Max Age Limit)