CPT/HCPCS
82784, 86364x4
Order Code
CH223
Turnaround Time
24-48 hours
Test Includes
Deamidated Gliadin Abs, IgA; Deamidated Gliadin Abs, IgG; t-Transglutaminase (tTG) IgA; t Transglutaminase (tTG) IgG; Immunoglobulin A
Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)
(Specimen Container)
SST (Tiger Top)
Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
(Transport Temperature)
Room Temperature
Specimen Stability
| Temperature | Period |
|---|---|
| Room temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 30 days |
Test Details
Methodology
Immunoassay, Immunoturbidimetric assay
Clinical Significance
Celiac disease is a gluten enteropathy occurring in both children and adults. The disease is probably underdiagnosed in that it may affect as much as 1% of the population in the US. The condition is characterized by a sensitivity to gluten (found in wheat, barley, and rye) that causes inflammation and atrophy of the villi of the small intestine, malabsorption, etc. This sensitivity to gluten may also be seen in dermatitis herpetiformis. Strict avoidance of gluten in the diet will control disease activity, and antibodies to serum markers will disappear with time.
Reference Ranges
See individual analytes
