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Varicella-Zoster Virus Antibody (IgG)

CPT/HCPCS 86787
Order Code CH321
Turnaround Time 24-48 hours
Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

Serum Separator Tube (SST)

Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Reject Criteria

Gross hemolysis
Grossly lipemic
Grossly icteric

Special Instructions

Separate serum from cells within 45 minutes of venipuncture.

Test Details
Methodology
Immunoassay (IA)
Clinical Significance

Varicella-zoster virus (VZV), a herpes virus, causes 2 exanthematous (rash-associated) diseases, chickenpox and herpes zoster (shingles). Chickenpox is a highly contagious disease usually contracted during childhood and is characterized by a dermal vesiculopustular rash that develops in successive crops. Although primary infection results in immunity to subsequent exposure to chickenpox, the virus remains latent in the body, localized to the dorsal root or cranial nerve ganglia. Reactivation of latent infection manifests as herpes zoster. On reactivation, the virus migrates along neural pathways to the skin, producing a unilateral rash usually limited to a single dermatome. Reactivation occurs in older adults and in patients with impaired cellular immunity.

Reference Ranges

≤ 1 Index