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Total Protein 24hr Urine

Order Code CH477
Turnaround Time 24 hours
Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

Plastic urine container

Preferred Specimens
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Acidified urine

Special Instructions

Instruct patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the following day). Mix well. Screw the lid on securely. Container must be labeled with patient’s name, date, total urine volume and time collection started and finished. 10 mL urine aliquot from a well-mixed, 24-hour collection – no preservative. Transport Refrigerated.

Test Details
Clinical Significance

Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands. Increased amounts of protein in the urine may be due to: -Glomerular proteinuria: caused by defects in permselectivity of the glomerular filtration barrier to plasma proteins (eg, glomerulonephritis or nephrotic syndrome) -Tubular proteinuria: caused by incomplete tubular reabsorption of proteins (eg, interstitial nephritis) -Overflow proteinuria: caused by increased plasma concentration of proteins (eg, multiple myeloma, myoglobinuria) -Urinary tract inflammation or tumor.

Reference Ranges

30 – 150 mg/24h