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Thyroglobulin Antibodies Panel

CPT/HCPCS 8,680,084,432
Order Code CH308
Turnaround Time 72 hours
Test Includes

Thyroglobulin Antibodies and Quantitative Thyroglobulin

Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

Serum Separator Tube (SST)

Preferred Specimens
Minimum Volume (uL)
0.5 mL
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 7 days
Frozen 28 days
Reject Criteria

Gross hemolysis, Gross lipemia

Test Details
Immunoassay (IA)
Clinical Significance

Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis. Deficient TG synthesis is observed in infants with goitrous hypo-thyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. With immunometric assays (sandwich assays), TGAB interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent antibodies from binding endogenous TG.

Reference Ranges

See individual tests