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Myoglobin

CPT/HCPCS 83874
Order Code CH168
Turnaround Time 24-48 hours
Test Includes

Myoglobin

Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

SST (Tiger Top)

Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 8 hours
Refrigerated 14 days
Frozen 30 days
Test Details
Methodology
Immunoassay (IA)
Clinical Significance

Assessing muscle damage from any cause. Myoglobin is a heme protein found in smooth and skeletal muscles. Serum myoglobin reflects a balance between intravascular release of myoglobin from muscle and renal clearance. Previously serum myoglobin had been advocated as a sensitive marker for early acute myocardial injury (eg, acute myocardial infarction: AMI). However, more recent studies indicate that other newer markers (eg, troponin) provide superior diagnostic utility in detecting early myocardial injury. Elevation of serum myoglobin may occur as a result of muscle trauma, resuscitation, myopathies, AMI, shock, strenuous body activity, or decreased elimination during renal insufficiency. Extreme elevations occur in rhabdomyolysis.

Reference Ranges

Male:
28 – 72 ng/mL

Female:
25 – 58 ng/mL