CPT/HCPCS
86021
Order Code
CH214
Turnaround Time
24-48 hours
Test Includes
Myeloperoxidase Antibody (MPO)
Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)
(Specimen Container)
SST (Tiger Top)
Preferred Specimens
Serum_x000D_
Collection Instructions
(Transport Temperature)
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
| Temperature | Period |
|---|---|
| Room temperature | Unacceptable |
| Refrigerated | 7 days |
| Frozen | 30 days |
Reject Criteria
Gross hemolysis
Test Details
Methodology
Immunoassay (IA)
Clinical Significance
Patients with vascular diseases will generally have either a C-ANCA pattern or P-ANCA pattern, and give positive results in specific tests for PR-3 or MPO. Patients with bowel disease have been shown to have antibodies that give a P-ANCA or C-ANCA pattern. These antibodies, however, may not be directed toward MPO. Patients with drug induced lupus, etc., often present with a P-ANCA pattern that is associated with antibodies against MPO.
Reference Ranges
< 1 AI_x000D_
Alternative Names
MPO
