CPT/HCPCS
82570, 83921
Order Code
CH496
Turnaround Time
7 days
Test Includes
Creatinine
Specimen Requirements
Specimen Source
24-hour urine • Random clean-catch
urine • Catheterized urine • First void
clean-catch_x000D_
Transport Container
(Specimen Container)
(Specimen Container)
Plastic urine container
Preferred Specimens
1.7 mL urine - no preservative
Minimum Volume (uL)
0.6 mL
Collection Instructions
(Transport Temperature)
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
| Temperature | Period |
|---|---|
| Room temperature | 4 days |
| Refrigerated | 12 days |
| Frozen | 30 days |
Reject Criteria
Received room temperature
Acidified urine
Test Details
Methodology
Gas Chromatography/Tandem Mass Spectrometry (GC/MS/MS)
Clinical Significance
Methylmalonic Acid, GC/MS/MS, Urine – Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B12 (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia.
Reference Ranges
Methylmalonic Acid, Urine 0.3-2.2 mmol/mol creat Creatinine, Random Urine:
0.18-2.48 mmol/L (0-6 Months)
0.18-2.74 mmol/L (7-11 Months)
0.18-9.72 mmol/L (1-2 Years)
0.18-11.49 mmol/L (3-8 Years)
0.18-14.14 mmol/L (9-12 Years)
1.77-23.31 mmol/L (>12 Years)
