If Islet Cell Antibody Screen is positive, then Islet Cell Antibody Titer will be performed at an additional charge (CPT code(s): 86341).
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
(Specimen Container)
Transport Tube
(Transport Temperature)
| Temperature | Period |
|---|---|
| Room temperature | 48 hours |
| Refrigerated | 14 days |
| Frozen | 6 months |
Gross hemolysis, Grossly lipemic, Grossly icteric
Fasting specimen in preferred
Islet Cell Antibody Screen with Reflex to Titer – Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type 1 diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.
Islet Cell Antibody Screen Negative
Islet Cell Antibody Titer <1.25 JDF units
