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Herpes Simplex Virus 1&2 Specific Ab IgG

CPT/HCPCS 86695, 86696
Order Code CH236
Turnaround Time 24-48 hours
Test Includes

HSV 1 IgG
HSV 2 IgG

Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

Serum Separator Tube (SST/Tiger Top)

Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Gross hemolysis
Grossly lipemic
Plasma

Test Details
Methodology
Immunoassay (IA)
Clinical Significance

Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients.

Reference Ranges

HSV 1 IgG: ≤ 0.9 index
HSV 2 IgG: ≤ 0.9 index