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Hepatitis B Virus RT PCR Quant w/reflex to Genotypes

Order Code CH497
Turnaround Time 9 - 11 days
Test Includes

If Hepatitis B Virus DNA, Quantitative, RealTime PCR is ≥600 IU/mL, then Hepatitis B Virus Drug Resistance, Genotype, and BCP/Precore Mutations will be performed at an additional charge (CPT code(s): 87912).

Specimen Requirements
Specimen Source
Serum, Plasma
Transport Container
(Specimen Container)

(2x) EDTA (lavender-top) tubes Alternative Specimen(s): Serum collected in each of two separate tubes

Preferred Specimens
Minimum Volume (uL)
1.4 mL in each tube
Collection Instructions
(Transport Temperature)
Transport Frozen
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 6 days
Frozen 30 days
Reject Criteria

Unspun SST tube
Sodium heparin (green-top) tube
Lithium heparin (green-top) tube

Test Details
Real-Time Polymerase Chain Reaction • Sequencing
Clinical Significance

Hepatitis B Virus DNA, Quantitative, PCR with Reflex to HBV, Genotype:
This test is intended for use in conjunction with clinical presentation and other laboratory markers for the clinical management of patients with chronic HBV infection undergoing antiviral therapy. The test can be used to measure HBV DNA levels at baseline and during treatment to aid in assessing response to treatment.

The cobas® HBV Test is not intended for use as a screening test for the presence of HBV in blood products or as a diagnostic test to confirm the presence of HBV infection.

Reportable range is 10 to 1,000,000,000 IU/mL
(1.00 to 9.00 Log IU/mL).
(1.00 Log IU/mL to 9.00 Log IU/mL).

Reference Ranges

Not Detected