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Gabapentin

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CPT/HCPCS 80164
Order Code CH701
Turnaround Time 4 days
Test Includes

Gabapentin

Specimen Requirements
Specimen Source
Serum, Plasma
Transport Container
(Specimen Container)

Red-top tube (no gel)
Alternative Specimen(s): Plasma collected in EDTA (lavender top) tube, sodium heparin (green-top) tube or lithium heparin (green-top) tube

Preferred Specimens
Serum
Minimum Volume (uL)
.5 mL
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 5 days
Refrigerated 12 days
Frozen 30 days
Reject Criteria

Gross hemolysis
Gel barrier/Serum Separator Tube (SST®)

Special Instructions

Separate serum or plasma from red cells as soon as possible; pipette or pour into plastic transport tube.
Draw sample 2 hours after last dose. Transport Room temperature.

Test Details
Methodology
Chromatography/Mass Spectrometry_x000D_
Clinical Significance

Gabapentin:
Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.

Reference Ranges

2.7-4.1: (peak) following a single dose of 900-1800 mg/day.

4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.

The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.