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G6PD Quant

CPT/HCPCS 82955
Order Code CH292
Turnaround Time 72 hours
Specimen Requirements
Specimen Source
Whole blood
Transport Container
(Specimen Container)

EDTA (lavender-top) tube

Preferred Specimens
1 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume (uL)
0.5 mL
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Specimen Stability
Temperature Period
Room temperature Unacceptable
Refrigerated 7 days
Frozen Unacceptable
Reject Criteria

Received frozen

Test Details
Methodology
Spectrophotometry (SP)
Clinical Significance

Glucose-6-Phosphate Dehydrogenase, Quantitative – Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in the world, affecting an estimated 400 million people worldwide [1]. It is more common in people of African, Mediterranean, and Asian descent. G6PD deficiency is an X-linked genetic disorder and, in general, affects males more than females. Severity ranges from mild to severe subtypes. Newborns with G6PD deficiency may have prolonged and more pronounced neonatal jaundice than other newborns. Adults with G6PD deficiency may have episodes of acute hemolytic anemia, and symptoms may include jaundice, fatigue, splenomegaly, and dark urine. Episodes may be induced by illness (infections), certain foods (fava beans), and particular medications (for example some sulfonamides and antimalarial drugs)[2]; therefore, some precautions may be recommended to avoid offending triggers.

Reference Ranges

4.6-13.5 U/g Hgb

Alternative Names
Glucose-6-Phosphate Dehydrogenase