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Epstein-Barr Virus Antibody Panel

CPT/HCPCS 86664, 86665x2
Order Code CH287
Turnaround Time 24-48 hours
Test Includes

Epstein-Barr Virus VCA Antibody (IgM), Epstein-Barr Virus VCA Antibody (IgG), Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG), EBV Interpretation Chart

Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

Serum Separator Tube (SST)

Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
Transport Refrigerated (cold packs)
Test Details
Methodology
Immunoassay (IA)
Clinical Significance

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals. VCA-IgG is typically detectable at clinical presentation, and persists for life. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.

Reference Ranges

See individual analytes