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Creatinine Clearance

Order Code L226
Turnaround Time 24 hours
Test Includes

Creatinine (serum and urine), Creatinine Clearance (calculation), eGFR

Specimen Requirements
Specimen Source
Transport Container
(Specimen Container)

10 mL aliquot from a well-mixed, 24h urine collection no preservative. And 1 Serum Separator Tube

Preferred Specimens
Urine & Serum
Collection Instructions
(Transport Temperature)
Transport at Room Temperature
Specimen Stability
Temperature Period
Room temperature 72 hours
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Grossly icteric serum

Special Instructions

Record total volume and collection duration on specimen container and test requisition. Indicate the patient’s height (in feet and inches) and weight (in lbs.) on test requisition. Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection in Serum Separator Tube (SST®). Transported Room Temperature.

Test Details
Clinical Significance

Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle.

Reference Ranges

80 – 120 mL/min