CPT/HCPCS
86200
Order Code
CH221
Turnaround Time
24-48 hours
Test Includes
CCP Antibodies IgG
Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)
(Specimen Container)
SST (Tiger Top)
Preferred Specimens
Serum
Collection Instructions
(Transport Temperature)
(Transport Temperature)
Refrigerated
Reject Criteria
Gross hemolysis • Gross lipemia
• Plasma
Test Details
Methodology
Immunoassay (IA)
Clinical Significance
A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from other patients than either the perinuclear autoantibody test or the test for rheumatoid factor. Approximately 70% of patients with Rheumatoid Arthritis are positive for Anti-CCP IgG, while only about 2% of random blood donors and disease controls subjects are positive.
Reference Ranges
0-3 IU/mL