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ANA Chromatin (Nucleosomal) Ab

CPT/HCPCS 86235
Order Code CH268
Turnaround Time 48-72 hrs
Specimen Requirements
Specimen Source
Serum
Transport Container
(Specimen Container)

Transport Tube

Preferred Specimens
2 mL Serum
Minimum Volume (uL)
0.5 mL
Collection Instructions
(Transport Temperature)
Room Temperature
Specimen Stability
Temperature Period
Room temperature 4 days
Refrigerated 7 days
Frozen 30 days
Reject Criteria

Gross hemolysis, Grossly lipemic, Grossly icteric

Test Details
Methodology
Immunoassay
Clinical Significance

Chromatin Antibody plays a central role in the autoimmune response in systemic lupus erythematosus (SLE). Approximately 90% of patients with SLE have sera that will exhibit reactivity to nucleosomes.

Reference Ranges

<1.0 AI Negative