CPT/HCPCS
84460
Order Code
CH106
Turnaround Time
24 hours
Test Includes
ALT
Specimen Requirements
Specimen Source
Serum/Plasma
Transport Container
(Specimen Container)
(Specimen Container)
SST (Tiger Top)
Lithium Heparin/ Sodium Heparin/ EDTA
Preferred Specimens
Serum
Minimum Volume (uL)
.5 mL
Collection Instructions
(Transport Temperature)
(Transport Temperature)
Refrigerate
Specimen Stability
| Temperature | Period |
|---|---|
| Room temperature | 3 days |
| Refrigerated | 7 days |
| Frozen | 60 days (-40°C) |
Test Details
Methodology
Enzymatic: NADH (without P-5'-P)
Clinical Significance
Alanine Aminotransferase (ALT), also referred to as glutamate pyruvate transaminase (GPT), is an enzyme involved in amino acid metabolism. It is found in many tissues, but the highest levels are found in liver and kidney tissues. Tissue destruction leads to the release of the intracellular enzyme into the circulating blood. Markedly elevated serum ALT levels may be found in a variety of diseases which involve the liver, such as hepatitis, mononucleosis, and cirrhosis. These very high levels of ALT are not usually observed in other disease processes, e.g., myocardial infarction; thus, ALT is regarded as a reasonably specific indicator of liver disease.
Reference Ranges
0 – 55 U/L
